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The Causes

What causes premature ejaculation (PE)?

In the past PE was thought to be purely psychological. Now doctors know PE can have a physical cause as it is associated with serotonin signals in the brain (like a brain messenger chemical) that control ejaculation.

Further knowledge about PE continues to increase. Scientists discovered variations in a gene controlling serotonin signalling that could be linked to PE and some drug treatments used for treating PE works by influencing the serotonin signalling pathway.